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Perio TherapyToxic bacteria in plaque can cause periodontal disease, also known as gum disease or gingivitis ? an infection of the supportive tissues of the mouth. This disease can cause tooth loss, breakdown of the soft tissues in the mouth and other significant problems. Santa Fe Dental evaluates your periodontal health and, if needed, help you make a decision on the appropriate treatments to restore the health of your gums and supportive tissues.